A Case of Combined Neuromyelitis Optica Spectrum Disorder and Demyelinating Neuropathy

Park, Sung Joo; Oh, Jung-Hwan; Kang, Sa-Yoon

J Mult Scler > Volume 9(2); 2018 > Article

Case Report

Journal of Multiple Sclerosis 2018;9(2):24-27.
Published online September 1, 2018.

시신경척수염범주질환과 탈수초신경병이 동반된 증례

박성주, 오정환, 강사윤

제주대학교 의학전문대학원 신경과학교실

A Case of Combined Neuromyelitis Optica Spectrum Disorder and Demyelinating Neuropathy

Sung Joo Park, Jung-Hwan Oh, Sa-Yoon Kang

Department of Neurology, Jeju National University School of Medicine, Jeju, Korea

Abstract

"Neuromyelitis optica spectrum disorder (NMOSD) is characterized by transverse myelitis or optic neuritis with anti-aquaporin 4 antibodies. Concurrent peripheral neuropathy is rare in NMOSD. Wepresent the case of a patient with NMOSD who was also affected with demyelinating neuropathy.Anti-aquaporin 4 antibodies or other undetermined humoral factors may have caused peripheralneuropathy. Further investigation of the pathogenesis of peripheral neuropathy with NMOSD isneeded. Journal of Multiple Sclerosis 9(2):24-27, 2018"

Key Words: Anti-aquaporin 4 antibody, Myelitis, Neuromyelitis optica, Optic neuritis